Using the advantages of interdisciplinary research, study the force-chemical-biology interaction in the process of system development and homeostasis maintenance from the multi-scale levels of molecules, cells, and tissues. And quantitatively explain the coordinated regulatory network of cells in the dynamic evolution of tissues, spanning micro to macro Dimension. Our project is starting from the essence of life phenomena, exploring the unknown frontiers of science, in order to deepen the understanding of the basic principles of human embryonic development, organ formation, tumor development, and other frontier scientific issues of physiology and pathology, and provide new ideas for clinical treatment and tissue engineering applications.